Rio BioNMR Network
Working as a team
Rio de Janeiro
© 2020 by Rio-BioNMR Network.
The Rio BioNMR network (RMN-Rio) has the goal to improve the infrastructure and catalyze protein structure and dynamics determination by NMR. We are centered at the National NMR Center at UFRJ (CNRMN). RMN-Rio research network comprises all protein NMR research groups located in Rio de Janeiro (NMR-Rio) and associate groups from other states, with the following objectives:
To improve the laboratory infrastructure, especially for the emerging groups.
To build an infrastructure for drug screening by NMR.
To build infrastructure for protein production on a large scale.
To employ the advances in structural biology as a tool to address important biological challenges such as cancer, infectious and parasitic diseases as well as in biotechnology.
NMR-Rio network will enable these groups to achieve greater impact and competitiveness in research and innovation.
The mission at the Covid-19 NMR consortium (https://covid19-nmr.de/)
We aim to contribute to the Covid19-NMR consortium assigning the resonances and determining the protein structures of SARS-CoV-2 and also investigating the drugability of those structures by small molecules. Our specific protein target is the nucleocapsid phosphoprotein and its interaction with regulatory regions of the genomic RNA. The resulting data will be made publically available by weekly updates throughout the project prior to publication.